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Is finasteride a cytotoxic drug and can induce DNA base excision repair. The clinical use of finasteride in male and is finasteride a cytotoxic drug female patients has been reported.[2] Drug Interaction Some interactions between finasteride and drugs are known as "inducible inhibition models". A list of active ingredients used in many male and female treatments has been compiled. The list shows which products contain the active ingredients that may interact with finasteride.[2] Alcohol Finasteride is known to have an alcohol inhibitory effect when used with alcohol. Therefore, long-term use of finasteride and its in the face of a prior history alcohol misuse or alcoholism finasteride london drugs should be discouraged.[Citation needed] Hematologic Conditions In animal studies, finasteride is known to enhance the effects of hematologic malignancies.[2,24] Therefore, if a patient was being treated for leukemia, he should be warned of the potential benefits and risks related to his cancer therapy while taking finasteride. Fibroids When patients are being treated for fibroids, they should be advised to stop using finasteride if they continue experiencing an increase in the size of their fibroids, particularly within the first year of therapy. In addition, patients should be warned to discontinue their treatment in the event they experience a tumor recurrence or relapse.[2] Hereditary Prostate Malignancies Finasteride has been associated with a decrease in serum prostate-specific antigen, a predictor of the risk developing prostate cancer and of the extent disease. However, it should be noted that was not found to significantly modify or predict progression to prostate cancer among patients who were treated for prostate cancer.[2,24] Prostate Cancer Finasteride is not generally considered a treatment for treatment-resistant prostate cancer. However, some urologic oncologists report an increase in prostate cancer their practice following initiation of finasteride therapy.[2] is known to induce apoptosis, or programmed cell death, in cultured prostate cancer cells.[2,25] Finasteride can induce cellular changes in prostate cells that promote tumor growth and progression.[2] Finasteride has also been shown to interfere with the normal cell growth cycle in prostate cancer cells.[2] Further research is necessary to determine the extent which finasteride will affect the growth cycle of prostate cancer.[2] Although there have been no well-controlled long-term studies for patients receiving finasteride prophylaxis and treatment of prostate cancer (or other diseases), the results of such studies have shown an adverse effect on the prostate, with a lower urinary excretion of prostatic fluid, an increase in fluid on palpation and blood measurements a higher risk for side effects. However, such changes were seen at doses used in the treatment of prostate cancer.[2] It is important to note that finasteride is not associated with a higher risk for death from prostate cancer and all causes in postmenopausal men. Therefore, the recommendation for men discount pharmacy warehouse online to continue taking finasteride (at doses appropriate to address prostate specific antigen and other risk factors) for their health will be met. The decision to discontinue treatment with finasteride in those men cancer does.

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